GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
---|---|---|---|---|---|---|---|---|---|---|---|
UVM | cis | rs1411478 | 1 | rs4652545 | chr1:180947608 | STX6 | chr1:180913175-180992046:- | -0.58 | -5.74 | 4.28E-7 | Progressive supranuclear palsy |
UVM | cis | rs1411478 | 1 | rs4652547 | chr1:180954089 | STX6 | chr1:180913175-180992046:- | -0.58 | -5.69 | 5.07E-7 | Progressive supranuclear palsy |
UVM | cis | rs1411478 | 1 | rs4652548 | chr1:180954130 | STX6 | chr1:180913175-180992046:- | -0.58 | -5.69 | 5.07E-7 | Progressive supranuclear palsy |
UVM | cis | rs8135828 | 1 | rs465742 | chr22:29959335 | CABP7 | chr22:30116344-30127818:+ | -1.05 | -5.75 | 4.14E-7 | Lipid traits |
UVM | cis | rs4660306 | 1 | rs4660306 | chr1:45978675 | CCDC163P | chr1:45960581-45965646:- | 0.76 | 7.9 | 1.28E-10 | Homocysteine levels |
UVM | cis | rs4660306 | 1 | rs4660870 | chr1:45995231 | CCDC163P | chr1:45960581-45965646:- | -0.72 | -7.65 | 3.27E-10 | Homocysteine levels |
UVM | cis | rs2564921 | 1 | rs4687701 | chr3:53121276 | RFT1 | chr3:53122503-53164470:- | 0.35 | 4.68 | 1.89E-5 | Height |
UVM | cis | rs8135828 | 1 | rs468795 | chr22:29955450 | CABP7 | chr22:30116344-30127818:+ | -1.03 | -6.84 | 6.87E-9 | Lipid traits |
UVM | cis | rs8135828 | 1 | rs468852 | chr22:29956156 | CABP7 | chr22:30116344-30127818:+ | -1.03 | -6.84 | 6.87E-9 | Lipid traits |
UVM | cis | rs8078723 | 1 | rs4794823 | chr17:38166265 | GSDMA | chr17:38119226-38134019:+ | -0.87 | -7.55 | 4.73E-10 | Neutrophil count;White blood cell count;C-reactive protein and white blood cell count |
UVM | cis | rs8078723 | 1 | rs4794824 | chr17:38179290 | GSDMA | chr17:38119226-38134019:+ | -0.87 | -7.59 | 4.1E-10 | Neutrophil count;White blood cell count;C-reactive protein and white blood cell count |
UVM | cis | rs8078723 | 1 | rs4795412 | chr17:38150604 | GSDMA | chr17:38119226-38134019:+ | -0.87 | -7.54 | 4.94E-10 | Neutrophil count;White blood cell count;C-reactive protein and white blood cell count |
UVM | cis | rs8078723 | 1 | rs4795415 | chr17:38157995 | GSDMA | chr17:38119226-38134019:+ | -0.87 | -7.55 | 4.73E-10 | Neutrophil count;White blood cell count;C-reactive protein and white blood cell count |
UVM | cis | rs8078723 | 1 | rs4795416 | chr17:38158133 | GSDMA | chr17:38119226-38134019:+ | -0.87 | -7.55 | 4.73E-10 | Neutrophil count;White blood cell count;C-reactive protein and white blood cell count |
UVM | cis | rs8078723 | 1 | rs4795418 | chr17:38164851 | GSDMA | chr17:38119226-38134019:+ | -0.87 | -7.55 | 4.73E-10 | Neutrophil count;White blood cell count;C-reactive protein and white blood cell count |